Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia.

@article{Sawada1999Interleukin10IB,
  title={Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia.},
  author={Misako Sawada and Akio Suzumura and Hiroshi Hosoya and Tohru Marunouchi and Toshiharu Toshi Nagatsu},
  journal={Journal of neurochemistry},
  year={1999},
  volume={72 4},
  pages={1466-71}
}
Microglia, macrophage-like cells in the CNS, are multifunctional cells; they play an important role in removal of dead cells or their remnants by phagocytosis in the CNS degeneration and are one of important cells in the CNS cytokine network to produce and respond to a variety of cytokines. The functions of microglia are regulated by inhibitory cytokines. We have reported the expression of interleukin (IL)-10, one of the inhibitory cytokines, and its receptor in mouse microglia; therefore, IL… CONTINUE READING
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