Interleukin-10 gene promoter polymorphisms and risk of gastric cancer in a Chinese population: single nucleotide and haplotype analyses.

@article{Pan2013Interleukin10GP,
  title={Interleukin-10 gene promoter polymorphisms and risk of gastric cancer in a Chinese population: single nucleotide and haplotype analyses.},
  author={Xiong-Fei Pan and Shu-juan Yang and Marie Loh and Yao Jian Xie and Yuan-yuan Wen and Zhi sheng Tian and He Huang and Hui Lan and Feng Chen and Richie Soong and Chun-xia Yang},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2013},
  volume={14 4},
  pages={
          2577-82
        }
}
OBJECTIVES Interleukin (IL) -10 is a potent cytokine with a dual ability to immunosuppress or immunostimulate. We aimed to explore the association of IL10 promoter polymorphisms with risk of gastric cancer (GC) in a Han population in Southwestern China. METHODS We enrolled 308 pairs of GC and control subjects from four hospitals and a community between October 2010 and August 2011 in a 1:1 matched case-control design. Demographic information was collected using a designed questionnaire. IL10… CONTINUE READING

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