Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats

@article{Ogura2012Interleukin10EI,
  title={Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats},
  author={Mieko Ogura and Masashi Urabe and Toshio Akimoto and Akira Onishi and Chiaki Ito and Tomoko Sezazake Ito and Tomohide Tsukahara and Hiroaki Mizukami and Akihiro Kume and Susumu Muto and Eiji Kusano and Keiya Ozawa},
  journal={Gene Therapy},
  year={2012},
  volume={19},
  pages={476-482}
}
Varying degrees of metabolic abnormalities mediated by chronic inflammation are implicated in the chronic glomerular injuries associated with obesity. Interleukin (IL)-10, a pleiotropic cytokine, exerts anti-inflammatory effects in numerous biological settings. In the present study, we explored the biological benefits of adeno-associated virus (AAV) vector… CONTINUE READING