Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development.

Abstract

Interleukin-10-deficient mice develop colitis and colorectal cancer similar to the inflammatory bowel disease associated cancer in humans. The aim of this study was to identify possible mutations of oncogenes and tumour suppressor genes involved in tumorigenesis in Interleukin-10 (IL-10)-deficient mice. Twenty colon carcinomas from IL-10-deficient mice were… (More)

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@article{turlan2001Interleukin10deficientMA, title={Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development.}, author={Sanda {\vS}turlan and Gerhard Oberhuber and Britta G Beinhauer and Brigitte Tichy and Stefanie Kappel and J. Wang and M. A. Rogy}, journal={Carcinogenesis}, year={2001}, volume={22 4}, pages={665-71} }