Interleukin-1 stimulates growth and inhibits progesterone secretion in cultures of porcine granulosa cells.

@article{Fukuoka1989Interleukin1SG,
  title={Interleukin-1 stimulates growth and inhibits progesterone secretion in cultures of porcine granulosa cells.},
  author={Muneyoshi Fukuoka and Kazuki Yasuda and Shunzou Taii and Kenji Takakura and Takahide Mori},
  journal={Endocrinology},
  year={1989},
  volume={124 2},
  pages={884-90}
}
Interleukin-1 (IL-1) significantly inhibited basal progesterone secretion and influenced the cell number in high density cultures of porcine granulosa cells harvested from small (1-2 mm) or medium (3-5 mm) follicles. These two effects of IL-1 showed similar but inverse dose-response relationships: Significant effects were observed at concentrations higher… CONTINUE READING