Interleukin-1 receptors on rat brain endothelial cells: a role in neuroimmune interaction?

@article{Dam1996Interleukin1RO,
  title={Interleukin-1 receptors on rat brain endothelial cells: a role in neuroimmune interaction?},
  author={A-M van Dam and Helga Eveline de Vries and J. J. W. Kuiper and Freek J. Zijlstra and Albertus G de Boer and Fred J. H. Tilders and F Berkenbosch},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={1996},
  volume={10 2},
  pages={351-6}
}
Inflammation following an infection induces a range of nonspecific symptoms of sickness in animals and humans. The cytokine interleukin-1 (IL-1) mediates many of the brain-mediated symptoms of sickness. Binding sites for IL-1 have been found in mouse brain, but not in the brains of rats. This raises questions as to the involvement of these neuronally… CONTINUE READING