Interleukin-1 receptor antagonist expression in the equine endometrium during the peri-implantation period.

@article{Haneda2009Interleukin1RA,
  title={Interleukin-1 receptor antagonist expression in the equine endometrium during the peri-implantation period.},
  author={Shingo Haneda and Keita Nagaoka and Yasuo Nambo and Masato Kikuchi and Yuka Nakano and Motozumi Matsui and Y Miyake and James N. MacLeod and Kazuhiko Imakawa},
  journal={Domestic animal endocrinology},
  year={2009},
  volume={36 4},
  pages={209-18}
}
To identify factors involved in the establishment of pregnancy in the mare, endometrium was collected from day 13 (day 0=day of ovulation) cyclic and day 13, 19, and 25 pregnant animals. From initial cDNA subtraction studies, interleukin-1 receptor antagonist (IL-1RN) mRNA was found as a candidate molecule expressed uniquely in the pregnant endometrium. Expression of IL-1RN mRNA was markedly increased in day 19 and 25 gravid endometrium. In situ hybridization analysis revealed that IL-1RN mRNA… CONTINUE READING
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