Interleukin 1 plus interleukin 3 plus colony-stimulating factor 1 are essential for clonal proliferation of primitive myeloid bone marrow cells.

@article{Bartelmez1989Interleukin1P,
  title={Interleukin 1 plus interleukin 3 plus colony-stimulating factor 1 are essential for clonal proliferation of primitive myeloid bone marrow cells.},
  author={Stephen H. Bartelmez and Tracey Bradley and Ivan Bertoncello and Diane Y. Mochizuki and Robert Tushinski and E Richard Stanley and Andrew J. Hapel and Ian G. Young and A. B. Kriegler and Graham S. Hodgson},
  journal={Experimental hematology},
  year={1989},
  volume={17 3},
  pages={240-5}
}
The clonal growth in nutrient agar at low cell densities of high-proliferative potential colony-forming cells (HPP-CFC) of bone marrow obtained from mice treated 2 days earlier with 5-fluorouracil (FU) (FU2dBM) has been shown to require a combination of three growth factors, interleukin 1 (IL-1), interleukin 3 (IL-3), and macrophage colony-stimulating factor (CSF-1). These HPP-CFC have been enriched 140-fold from FU2dBM by fluorescence-activated cell sorting of 7/4-, B220-, and L3T4-negative… CONTINUE READING
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