Interleukin-1 family cytokines and their regulatory proteins in normal pregnancy and pre-eclampsia.


Maternal systemic inflammation is a feature of pre-eclampsia, a condition in pregnancy characterized by hypertension and proteinuria. Pre-eclampsia is caused by the placenta; many placental factors contribute to the syndrome's progression, and proinflammatory cytokines have been identified previously as one such mediator. The interleukin (IL)-1 family of… (More)
DOI: 10.1111/cei.12608