Interleukin-1 beta targeted therapy for type 2 diabetes.

  title={Interleukin-1 beta targeted therapy for type 2 diabetes.},
  author={Kathrin Maedler and Gitanjali Dharmadhikari and Desiree M. Schumann and Joachim St\orling},
  journal={Expert opinion on biological therapy},
  volume={9 9},
Since having been cloned in 1984, IL-1beta has been the subject of over 22,000 citations in Pubmed, among them over 800 reviews. This is because of its numerous effects. IL-1beta is a regulator of the body's inflammatory response and is produced after infection, injury, and antigenic challenge. It plays a role in various diseases, including autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases and type 1 diabetes, as well as in diseases associated with metabolic syndrome… CONTINUE READING


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