Interleukin-1 beta induces interleukin-6 mRNA expression and protein production in synovial cells from human temporomandibular joint.

@article{Ogura2002Interleukin1BI,
  title={Interleukin-1 beta induces interleukin-6 mRNA expression and protein production in synovial cells from human temporomandibular joint.},
  author={Naomi Ogura and Makiko Tobe and Hiroyuki Sakamaki and Hiroaki Kujiraoka and Masakazu Akiba and Yoshimitsu Abiko and Hideaki Nagura},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2002},
  volume={31 6},
  pages={353-60}
}
BACKGROUND Interleukin (IL)-1 beta and IL-6 were found to be elevated in fluid from the temporomandibular joint (TMJ), although the source of these cytokines was not elucidated. There is little known about the function and response of synovial cells in the TMJ. The purpose of this study was to prepare cultured human synovial cells (HTS cells) from the TMJ and to investigate IL-6 production in HTS cells incubated with IL-1 beta. METHODS HTS cells were isolated from temporomandibular joint… CONTINUE READING

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