Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells.

@article{Zoja1991Interleukin1BA,
  title={Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells.},
  author={Carlamaria Zoja and Ji ming Wang and Stefania Bettoni and Marina Sironi and Daniela Renzi and Francesca Chiaffarino and Hanna Emily Abboud and Jo Van Damme and Alberto Mantovani and Giuseppe Remuzzi},
  journal={The American journal of pathology},
  year={1991},
  volume={138 4},
  pages={991-1003}
}
The capacity of human cultured mesangial cells to produce soluble factors potentially relevant for mechanisms of inflammation and immunity at the glomerular site was analyzed. The nature of the secreted factors initially was investigated by Northern blot analysis using total cellular RNAs isolated from resting and activated mesangial cells. On exposure of… CONTINUE READING