Interleukin-1β (IL-1β) increases pain behavior and the blood glucose level: possible involvement of glucocorticoid system.

@article{Sim2013Interleukin1I,
  title={Interleukin-1β (IL-1β) increases pain behavior and the blood glucose level: possible involvement of glucocorticoid system.},
  author={Y Y Sim and Soo-Hyun Park and Yu-Jung Kang and J Jung and Ohk-Hyun Ryu and Moon-Gi Choi and Seong-Soo Choi and H K D H Suh},
  journal={Cytokine},
  year={2013},
  volume={64 1},
  pages={351-6}
}
The possible involvement of glucocorticoid system in interleukin-1β (IL-1β)-induced nociception and the blood glucose level was studied in ICR mice. In the first experiment, mice were treated intrathecally (i.t.) with IL-1β (100 pg). Corticotrophin releasing hormone (CRH) mRNA (hypothalamus) and c-Fos mRNA (pituitary gland, spinal cord, and the adrenal gland) levels were measured at 30, 60 and 120 min after IL-1β administration. We found that i.t. injection with IL-1β increased CRH mRNA level… CONTINUE READING

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Corticotrophin releasing hormone ( CRH ) mRNA ( hypothalamus ) and c - Fos mRNA ( pituitary gland , spinal cord , and the adrenal gland ) levels were measured at 30 , 60 and 120 min after IL-1β administration .
Corticotrophin releasing hormone ( CRH ) mRNA ( hypothalamus ) and c - Fos mRNA ( pituitary gland , spinal cord , and the adrenal gland ) levels were measured at 30 , 60 and 120 min after IL-1β administration .
Corticotrophin releasing hormone ( CRH ) mRNA ( hypothalamus ) and c - Fos mRNA ( pituitary gland , spinal cord , and the adrenal gland ) levels were measured at 30 , 60 and 120 min after IL-1β administration .
Corticotrophin releasing hormone ( CRH ) mRNA ( hypothalamus ) and c - Fos mRNA ( pituitary gland , spinal cord , and the adrenal gland ) levels were measured at 30 , 60 and 120 min after IL-1β administration .
GonadorelinGene product expressed in tissueHypothalamic structure
Corticotrophin releasing hormone ( CRH ) mRNA ( hypothalamus ) and c - Fos mRNA ( pituitary gland , spinal cord , and the adrenal gland ) levels were measured at 30 , 60 and 120 min after IL-1β administration .
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