Interleukin-1, immune activation pathways, and different mechanisms in osteoarthritis and rheumatoid arthritis.

@article{Kirkham1991Interleukin1IA,
  title={Interleukin-1, immune activation pathways, and different mechanisms in osteoarthritis and rheumatoid arthritis.},
  author={Brenda Kirkham},
  journal={Annals of the rheumatic diseases},
  year={1991},
  volume={50 6},
  pages={395-400}
}
The properties of interleukin-l suggest that it has a central role in the immunopathology of many arthritides (figure). It is now more than 10 years since it was realised that numerous biological activities were due to a single agent called interleukin-I (IL-I)' (now known to be two related proteins, IL-la and IL-l132). The functions of IL-1, such as T cell activation,3 stimulation of cellular production of prostaglandin E2 and I2,4 interleukin-1,5 and interleukin-6,6 help for B cell growth,7… CONTINUE READING

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Change in interleukin 1 beta expression in rheumatoid synovial membrane after treatment with gold and glucocorticoid [ Abstract ]

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Detection of ILla and IL - 1 i in the supernatants of paraformaldehydetreated human monocytes . Evidence against a membrane form of IL - 1

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