Interleukin-1&; and interleukin-6 in the urine, kidney, and bladder of mice inoculated with Escherichia coli

@article{Tullus1996Interleukin1AI,
  title={Interleukin-1&; and interleukin-6 in the urine, kidney, and bladder of mice inoculated with Escherichia coli},
  author={Kjell Tullus and Ji-an Wang and Ying Lu and Lars G. Burman and Annelie Brauner},
  journal={Pediatric Nephrology},
  year={1996},
  volume={10},
  pages={453-457}
}
After bladder inoculation of mice using the pyelonephritogenic Escherichia coli strain DS17, urinary interleukin-1α (IL-1α) peaked at 0.5 h post infection (mean 233 pg/ml), interleukin-6 (IL-6) at 2 h (mean 572 pg/ml), and leukocyturia at 4 h, all three persisting for more than 24 h. In the kidneys IL-1α peaked at 2 h, persisted over 24 h (mean 900 – 1,000 pg/ml), and decreased over 2 – 6 days post inoculation to a mean value of 208 pg/ml. Control kidneys showed low IL-1α values. IL-6 in the… CONTINUE READING

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Interleukin 1α and interleukin-1 receptor antagonist in the urine of children with acute pyelonephritis

  • K Tullus, O Fituri, LG Burman, B Wretlind, A Brauner
  • Acta Paediatr
  • 1996
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