Interleukin‐9 polymorphism in infants with respiratory syncytial virus infection: An opposite effect in boys and girls

@article{Schuurhof2010Interleukin9PI,
  title={Interleukin‐9 polymorphism in infants with respiratory syncytial virus infection: An opposite effect in boys and girls},
  author={Annemieke Schuurhof and Louis Bont and Christine L. E. Siezen and Hennie M. Hodemaekers and Hans C van Houwelingen and Tjeerd G. Kimman and Barbara Hoebee and Jan L. L. Kimpen and Riny Janssen},
  journal={Pediatric Pulmonology},
  year={2010},
  volume={45}
}
The predominance of severe respiratory syncytial virus (RSV) bronchiolitis in boys compared to girls is well known, but its mechanism is not yet understood. This is the first study focusing on gender‐specific genetic factors affecting the risk of severe RSV infection using a previously described cohort. We determined 347 single‐nucleotide polymorphisms (SNPs) in 470 children hospitalized for RSV infection, their parents, and 1,008 random population controls. We tested if these SNPs exerted a… 
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