Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay.

Abstract

An international, multi-lab trial was conducted to evaluate a flow cytometry-based method for scoring micronuclei in mouse lymphoma L5178Y cells [S.L. Avlasevich, S.M. Bryce, S.E. Cairns, S.D. Dertinger, In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability… (More)
DOI: 10.1016/j.mrgentox.2007.11.006

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