Interim estimates of 2016/17 vaccine effectiveness against influenza A(H3N2), Canada, January 2017

@inproceedings{Skowronski2017InterimEO,
  title={Interim estimates of 2016/17 vaccine effectiveness against influenza A(H3N2), Canada, January 2017},
  author={Danuta M. Skowronski and Catharine Tamara Chambers and Suzana Sabaiduc and J. Albert Dickinson and Amanda K. Winter and Gaston De Serres and Steven J Drews and Agatha Natalie Jassem and Jonathan B. Gubbay and Hugues Charest and Robert F Balshaw and Nathalie Bastien and Yan H Li and Mel Krajden},
  booktitle={Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin},
  year={2017}
}
Using a test-negative design, the Canadian Sentinel Practitioner Surveillance Network (SPSN) assessed interim 2016/17 influenza vaccine effectiveness (VE) against dominant influenza A(H3N2) viruses considered antigenically matched to the clade 3C.2a vaccine strain. Sequence analysis revealed substantial heterogeneity in emerging 3C.2a1 variants by province and over time. Adjusted VE was 42% (95% confidence interval: 18-59%) overall, with variation by province. Interim virological and VE… CONTINUE READING

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