Interictal seizure resections show two configurations of endothelial Glut1 glucose transporter in the human blood-brain barrier.

@article{Cornford1998InterictalSR,
  title={Interictal seizure resections show two configurations of endothelial Glut1 glucose transporter in the human blood-brain barrier.},
  author={Eain Maxwell Cornford and Shigeyo Hyman and Marcia E. Cornford and Elliot M. Landaw and Antonio V Delgado-Escueta},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={1998},
  volume={18 1},
  pages={
          26-42
        }
}
Immunogold electron microscopy was used to analyze and quantify the Glut1 glucose transporter in brain tissue from five patients undergoing surgery for treatment of seizures. Samples were prepared from two different regions of each resection: (1) the most actively spiking epileptogenic site, and (2) the least actively spiking region, as indicated by intraoperative EEG monitoring. Two configurations of endothelial cell Glut1 were observed. About one half of the capillary profiles examined… CONTINUE READING
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