Interictal epileptiform activity outside the seizure onset zone impacts cognition

@article{Ung2017InterictalEA,
  title={Interictal epileptiform activity outside the seizure onset zone impacts cognition},
  author={H. Ung and Christian Cazares and A. Nanivadekar and L. Kini and Joost B. Wagenaar and D. Becker and A. Krieger and T. Lucas and B. Litt and K. Davis},
  journal={Brain},
  year={2017},
  volume={140},
  pages={2157–2168}
}
See Kleen and Kirsch (doi:10.1093/awx178) for a scientific commentary on this article.Cognitive deficits are common among epilepsy patients. In these patients, interictal epileptiform discharges, also termed spikes, are seen routinely on electroencephalography and believed to be associated with transient cognitive impairments. In this study, we investigated the effect of spikes on memory encoding and retrieval, taking into account the spatial distribution of spikes in relation to the seizure… Expand
Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset.
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