Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene

@article{Martens2004IntergenicTI,
  title={Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene},
  author={Joseph A. Martens and Lisa Laprade and Fred Winston},
  journal={Nature},
  year={2004},
  volume={429},
  pages={571-574}
}
Transcription by RNA polymerase II in Saccharomyces cerevisiae and in humans is widespread, even in genomic regions that do not encode proteins. The purpose of such intergenic transcription is largely unknown, although it can be regulatory. We have discovered a role for one case of intergenic transcription by studying the S. cerevisiae SER3 gene. Our previous results demonstrated that transcription of SER3 is tightly repressed during growth in rich medium. We now show that the regulatory region… 
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