Intergenic transcription by RNA polymerase II coordinates Pol IV and Pol V in siRNA-directed transcriptional gene silencing in Arabidopsis.

@article{Zheng2009IntergenicTB,
  title={Intergenic transcription by RNA polymerase II coordinates Pol IV and Pol V in siRNA-directed transcriptional gene silencing in Arabidopsis.},
  author={Binglian Zheng and Zhengming Wang and Shengben Li and Bin Yu and Jinyuan Liu and Xuemei Chen},
  journal={Genes & development},
  year={2009},
  volume={23 24},
  pages={2850-60}
}
Intergenic transcription by RNA Polymerase II (Pol II) is widespread in plant and animal genomes, but the functions of intergenic transcription or the resulting noncoding transcripts are poorly understood. Here, we show that Arabidopsis Pol II is indispensable for endogenous siRNA-mediated transcriptional gene silencing (TGS) at intergenic low-copy-number loci, despite the presence of two other polymerases-Pol IV and Pol V-that specialize in TGS through siRNAs. We show that Pol II produces… CONTINUE READING
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