Intergenerational Effect of Early Life Exposure to Permethrin: Changes in Global DNA Methylation and in Nurr1 Gene Expression

@inproceedings{Bordoni2015IntergenerationalEO,
  title={Intergenerational Effect of Early Life Exposure to Permethrin: Changes in Global DNA Methylation and in Nurr1 Gene Expression},
  author={Laura Bordoni and Cinzia Nasuti and Maria Mirto and Fabio Caradonna and Rosita Gabbianelli},
  booktitle={Toxics},
  year={2015}
}
Environmental exposure to pesticides during the early stages of development represents an important risk factor for the onset of neurodegenerative diseases in adult age. Neonatal exposure to Permethrin (PERM), a member of the family of synthetic pyrethroids, can induce a Parkinson-like disease and cause some alterations in striatum of rats, involving both genetic and epigenetic pathways. Through gene expression analysis and global DNA methylation assessment in both PERM-treated parents and… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Early life permethrin treatment induces in striatum of older rats changes in α-synuclein content

D. Fedeli, M. Montani, C Nasuti, R. Gabbianelli
J. Nutrigenet. Nutrigenom • 2014
View 1 Excerpt

Similar Papers

Loading similar papers…