Interferons in relapsing remitting multiple sclerosis: a systematic review.

@article{Filippini2003InterferonsIR,
  title={Interferons in relapsing remitting multiple sclerosis: a systematic review.},
  author={Graziella Filippini and Luca Maria Munari and Barbara Incorvaia and George Cornell Ebers and Chris Polman and R D'amico and George P. Rice},
  journal={Lancet},
  year={2003},
  volume={361 9357},
  pages={
          545-52
        }
}
BACKGROUND Recombinant interferons have been approved by many national regulatory agencies for treatment of relapsing remitting multiple sclerosis, but widespread discussion continues about their true effectiveness, benefits, side-effects, and costs. METHODS With the Cochrane Collaboration methodology, we reviewed all published, randomised, placebo-controlled trials of recombinant interferons undertaken in patients with relapsing remitting multiple sclerosis between 1993 and 2002. Our primary… CONTINUE READING

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