Interferons in enteroviral heart disease: modulation of cytokine expression and antiviral activity


Interferon (IFN)-β has a more than 120-fold higher antiviral activity than the closely related IFN-α in human myocardial fibroblasts infected with the cardiotropic enterovirus coxsackievirus B3 (CVB3). CVB3 replication induces interleukin (IL)-6 and IL-8 expression in myocardial fibroblasts, and suppresses the expression of monocyte chemoattractant protein… (More)
DOI: 10.1007/s00430-003-0200-3


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