Interferons and viral infections

@article{Fensterl2009InterferonsAV,
  title={Interferons and viral infections},
  author={Volker Fensterl and Ganes C Sen},
  journal={BioFactors},
  year={2009},
  volume={35}
}
Interferons represent a family of cytokines, which is of central importance in the innate immune response to virus infections. All interferons act as secreted ligands of specific cell surface receptors, eliciting the transcription of hundreds of interferon‐stimulated genes whose protein products have antiviral activity, as well as antimicrobial, antiproliferative/antitumor, and immunomodulatory effects. Expression of type I and III interferons is induced in virtually all cell types upon… Expand
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