Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.

Abstract

The effect of a variety of cytokines on lipid metabolism in 3T3 L1 mouse fibroblasts and adipocytes was studied. Uptake of [3H]acetate by adipocytes and heparin-releasable lipoprotein lipase activity was inhibited after treatments of the cells with picomolar concentrations of recombinant human tumor necrosis factor alpha (rHuTNF-alpha), human tumor necrosis… (More)

Topics

7 Figures and Tables

Cite this paper

@article{Patton1986InterferonsAT, title={Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.}, author={J. S. Patton and Hana Shepard and Helena Wilking and G. Lewis and Bhawna Aggarwal and Thomas E Eessalu and Laurence A Gavin and C. M. Grunfeld}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1986}, volume={83 21}, pages={8313-7} }