Interferons, Mx genes, and resistance to influenza virus.

  title={Interferons, Mx genes, and resistance to influenza virus.},
  author={Michel Andr{\'e} Horisberger},
  journal={American journal of respiratory and critical care medicine},
  volume={152 4 Pt 2},
Human influenza is primarily an infection of the upper respiratory tract and central airways. The interferon (IFN) system appears to have a role in limiting viral spread and initiating recovery before the development of T-cell and B-cell responses in primary infection. All cellular responses to IFNs result from interaction with cell surface receptors that trigger the expression of a number of cellular genes. Among the IFN-inducible gene products, the Mx proteins have attracted much attention… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 29 extracted citations

Similar Papers

Loading similar papers…