Interferon-stimulated genes and their antiviral effector functions.

Abstract

Many viruses trigger the type I interferon (IFN) system, leading to the transcription of hundreds of interferon-stimulated genes (ISGs). The products of these ISGs exert numerous antiviral effector functions, many of which are still not fully described. Recent efforts have been aimed at identifying which ISGs are antiviral and further characterizing their… (More)
DOI: 10.1016/j.coviro.2011.10.008

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