Interferon-signaling pathway: associations with colon and rectal cancer risk and subsequent survival.

@article{Slattery2011InterferonsignalingPA,
  title={Interferon-signaling pathway: associations with colon and rectal cancer risk and subsequent survival.},
  author={Martha L. Slattery and Abbie Lundgreen and Kristina L Bondurant and Roger K Wolff},
  journal={Carcinogenesis},
  year={2011},
  volume={32 11},
  pages={1660-7}
}
Interferons (IFNs) are proteins involved in many functions including antiviral and antimicrobial response, apoptosis, cell cycle control and mediating other cytokines. IFN gamma (IFNG) is a proinflammatory cytokine that modulates many immune-related genes. In this study we examine genetic variation in IFNG, IFNGR1, IFNGR2 and interferon regulatory factors (IRFs) to determine associations with colon and rectal cancer and survival after diagnosis. We include data from two population-based… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

Identification of Critical Genes and Five Prognostic Biomarkers Associated with Colorectal Cancer

Medical science monitor : international medical journal of experimental and clinical research • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 33 references

DeltaNp 63 alpha / IRF 6 interplay activates NOS 2 transcription and induces autophagy upon tobacco exposure

S. P. Hussain
2011

Genetic variation in the TGF { beta } - signaling pathway and colon and rectal cancer risk

M. L. Slattery
Cancer Epidemiol . Biomarkers Prev . • 2011

Association between interleukin-4R and TGF-β1 gene polymorphisms and the risk of colorectal cancer in a Korean population.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland • 2010

Colorectal cancer risk prediction tool for white men and women without known susceptibility.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2009

Similar Papers

Loading similar papers…