Interferon regulatory factor-1 mediates interferon-gamma-induced apoptosis in ovarian carcinoma cells.

@article{Kim2002InterferonRF,
  title={Interferon regulatory factor-1 mediates interferon-gamma-induced apoptosis in ovarian carcinoma cells.},
  author={Eun-Joo Kim and J Lee and Sung-Eun Namkoong and S J Um and Jong-sup Park},
  journal={Journal of cellular biochemistry},
  year={2002},
  volume={85 2},
  pages={369-80}
}
Interferon-gamma (IFN-gamma), as one of interferon family that regulates antiviral, antiproliferative, and immunomodulatory responses, has been implicated for the growth regulation of ovarian cancer cells. However, the molecular mechanisms are not yet fully defined. To analyze detailed mechanisms, the ovarian cancer cell lines (2774, PA-1, OVCAR-3, and SKOV-3) were treated with IFN-gamma. The growth of 2774 was most effectively suppressed than that of other cells in both time-course and dose… CONTINUE READING

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Interferon regulatory factor-1 mediates interferon - gamma - induced apoptosis in ovarian carcinoma cells .
Interferon regulatory factor-1 mediates interferon - gamma - induced apoptosis in ovarian carcinoma cells .
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