Interferon regulatory factor-1 exerts inhibitory effect on neointimal formation after vascular injury.

@article{Li2009InterferonRF,
  title={Interferon regulatory factor-1 exerts inhibitory effect on neointimal formation after vascular injury.},
  author={Zhen Li and Zhong Wang and Chaochao Bian and Xiao-Dong Chen and Jian-wen Li and Xiu Chen and Bing Han and Gao-feng Hou and Jian Chu and Qi Qi Cui},
  journal={Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih},
  year={2009},
  volume={24 2},
  pages={91-6}
}
OBJECTIVE To investigate the effect of interferon regulatory factors (IRFs) on neointimal formation after vascular injury in the mouse, and its possible mechanism. METHODS Vascular injury was induced by polyethylene cuff placement around the left femoral artery of IRF-1-deficient mice and C57BL/6J mice. The mRNA expressions of IRF-1, IRF-2, angiotensin II type 2 (AT2) receptor, interleukin-1 beta converting enzyme (ICE), inducible nitric oxide synthase (iNOS) were detected by RT-PCR and… CONTINUE READING

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