Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response.

@article{Wang1996InterferoninduciblePI,
  title={Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response.},
  author={Xin Wang and Tian-li Yue and Eliot H. Ohlstein and C. P. Sung and Giora G Z Feuerstein},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 39},
  pages={24286-93}
}
Interferon-inducible protein-10 (IP-10) is a member of the C-X-C chemokine family. Using mRNA differential display, we isolated a rat homologue to murine and human IP-10 from lipopolysaccharide-stimulated carotid arteries. Our studies demonstrated that IP-10 is a potent mitogenic and chemotactic factor for vascular smooth muscle cells, the critical features of smooth muscle cells for their contribution to the pathogenesis of atherosclerosis and restenosis. IP-10 induced a concentration… CONTINUE READING

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