Interferon-inducible factor 16 is a novel modulator of glucocorticoid action

  title={Interferon-inducible factor 16 is a novel modulator of glucocorticoid action},
  author={Andy Berry and Lesley Matthews and Maryam Jangani and Julie Plumb and Stuart Farrow and Nina Buchan and Paul A. Wilson and Dave Singh and David W Ray and Rachelle P. Donn},
  journal={The FASEB Journal},
  pages={1700 - 1713}
Previously, we used cDNA expression profiling to identify genes associated with glucocorticoid (Gc) sensitivity. We now identify which of these directly influence Gc action. Interferon-inducible protein 16 (IFI16), bone morphogenetic protein receptor type II (BMPRII), and regulator of G-protein signaling 14 (RGS14) increased Gc transactivation, whereas sialyltransferase 4B (SIAT4B) had a negative effect. Amyloid beta (A4) precursor-protein binding, family B, member 1 (APBB1/Fe65) and neural… CONTINUE READING