Interferon induces morphologic reversion with elimination of extrachromosomal viral genomes in bovine papillomavirus-transformed mouse cells.

Abstract

The effect of mouse L-cell interferon on bovine papillomavirus type 1 (BPV-1) transformation of murine cells was examined. Mouse interferon reduced the level of BPV-1-induced transformation of mouse C127 cells by 95%. Long-term treatment of established BPV-1-transformed mouse cell clones with mouse L-cell interferon led to a decrease in the average number… (More)

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@article{Turek1982InterferonIM, title={Interferon induces morphologic reversion with elimination of extrachromosomal viral genomes in bovine papillomavirus-transformed mouse cells.}, author={Lubomir P. Turek and Jennifer C. Byrne and Douglas R Lowy and Israel Dvoretzky and Robert M. Friedman and Peter M. Howley}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1982}, volume={79 24}, pages={7914-8} }