Interferon-induced Mx proteins in antiviral host defense.

  title={Interferon-induced Mx proteins in antiviral host defense.},
  author={Otto Haller and Peter Staeheli and Georg Kochs},
  volume={89 6-7},
Mx proteins are key components of the antiviral state induced by interferons in many species. They belong to the class of dynamin-like large guanosine triphosphatases (GTPases) known to be involved in intracellular vesicle trafficking and organelle homeostasis. Mx GTPases share structural and functional properties with dynamin, such as self-assembly and… CONTINUE READING