Interferon in chronic myeloid leukaemia: past and future.

@article{Guilhot2009InterferonIC,
  title={Interferon in chronic myeloid leukaemia: past and future.},
  author={François Guilhot and Lydia Roy and Pierre-Jean Saulnier and Jo{\"e}lle Guilhot},
  journal={Best practice & research. Clinical haematology},
  year={2009},
  volume={22 3},
  pages={315-29}
}
Imatinib has revolutionized the therapy of chronic myeloid leukaemia. However the complete eradication of leukaemic stem cells is still a matter of discussion. Interferon (IFN) has been used in the past with success. However the proportion of patients who achieved sustained complete cytogenetic response was small. Recently, in addition to its direct antineoplastic effect and immunomodulatory activity, IFN has been shown to stimulate the quiescent leukaemic stem cells. Thus there is now a… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Beyond tyrosine kinase inhibitors: Combinations and other agents.

Best practice & research. Clinical haematology • 2016
View 1 Excerpt

Interferon-alpha in chronic myeloid leukemia revisited: a long-term retrospective study in Central and Northern Moravia.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia • 2013

Similar Papers

Loading similar papers…