Interferon gamma release assay for differentiating tuberculosis among pneumonia cases in acute healthcare setting.

@article{Lui2011InterferonGR,
  title={Interferon gamma release assay for differentiating tuberculosis among pneumonia cases in acute healthcare setting.},
  author={Grace Chung-Yan Lui and Nelson Lee and Siu Wai Cheung and Judy Suk Yee Lam and Bonnie Chun Kwan Wong and Kin Choi and Ka Tak Wong and Rity Y. K. Wong and Clive Stewart Cockram and David Shu Cheong Hui and Robert C. Chan},
  journal={The Journal of infection},
  year={2011},
  volume={62 6},
  pages={440-7}
}
OBJECTIVES Early diagnosis of smear-negative tuberculosis remains challenging. The role of an interferon-gamma release assay (IGRA) in discriminating active pulmonary tuberculosis (PTB) among cases of 'pneumonia' was investigated. METHODS Consecutive patients admitted to an acute hospital in Hong Kong (intermediate TB burden) during 2006-2008 because of pneumonia and suspected PTB were recruited for IGRA (Quantiferon-TB Gold, QFN-G) study. Diagnosis of tuberculosis was confirmed by… CONTINUE READING