Interferon-gamma regulation of intestinal epithelial permeability.

  title={Interferon-gamma regulation of intestinal epithelial permeability.},
  author={C{\'e}cile Beaurepaire and David H. Smyth and D M McKay},
  journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research},
  volume={29 3},
The maintenance and regulation of the barrier function of the epithelial lining of the intestine are important homeostatic events, serving to allow selective absorption from the gut lumen while simultaneously limiting the access of bacteria into the mucosa. Interferon-gamma is a pleiotrophic cytokine produced predominantly by natural kill cells and CD4+ T cells that under normal circumstances, and particularly during infection or inflammation, will be a component of the intestinal milieu. Use… CONTINUE READING

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