Interferon-gamma production of mitogen stimulated peripheral lymphocytes in perinatal cows.


The production of interferon-gamma (IFN-gamma) in bovine peripheral blood mononuclear cells (PBMC) during the perinatal period was studied. IFN-gamma activity was neutralized with monoclonal antibodies (MoAb) to recombinant bovine IFN-gamma. IFN-gamma production was apparently suppressed by treatment of the PBMC with MoAb to bovine pan-T cell. IFN-gamma was… (More)