Interferon-gamma production by peripheral blood mononuclear cells of patients with chronic liver disease.

@article{Fuji1987InterferongammaPB,
  title={Interferon-gamma production by peripheral blood mononuclear cells of patients with chronic liver disease.},
  author={Akihiko Fuji and Shinichi Kakumu and Yoshiyuki Ohtani and Kenichi Murase and Hideo Hirofuji and Hirofumi Tahara},
  journal={Hepatology},
  year={1987},
  volume={7 3},
  pages={577-81}
}
We investigated the role of the interferon system in the pathogenesis of chronic liver disease. Interferon-gamma production by peripheral blood mononuclear cells was measured with an ELISA. While concanavalin A-stimulated and recombinant interleukin 2-stimulated production of interferon-gamma in patients with chronic active hepatitis and liver cirrhosis was significantly decreased when compared with that of controls (518 +/- 189 and 729 +/- 195 units per ml, mean +/- S.D.), there was also a lot… CONTINUE READING

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