Interferon-gamma counteracts reduced endotoxin responsiveness of whole blood following trauma and cardiopulmonary bypass.

@article{Floh2000InterferongammaCR,
  title={Interferon-gamma counteracts reduced endotoxin responsiveness of whole blood following trauma and cardiopulmonary bypass.},
  author={Stefanie B. Floh{\'e} and Jochen Boergermann and Lorena Lim and Fritz Ulrich Schade},
  journal={Journal of endotoxin research},
  year={2000},
  volume={6 6},
  pages={431-6}
}
Accidental as well as surgical trauma has been reported to cause reduced endotoxin responsiveness of blood in terms of cytokine production. In this study, the effect of interferon-gamma (IFN-gamma) on tumour necrosis factor-alpha (TNF-alpha)-producing capacity of whole blood after severe trauma and cardiac surgery was investigated. Blood samples of severely… CONTINUE READING