Interferon-gamma (IFN-γ): Exploring its implications in infectious diseases
@article{Kak2018InterferongammaE, title={Interferon-gamma (IFN-$\gamma$): Exploring its implications in infectious diseases}, author={Gunjan Kak and Mohsin Raza and Brijendra Kumar Tiwari}, journal={Biomolecular Concepts}, year={2018}, volume={9}, pages={64 - 79} }
Abstract A key player in driving cellular immunity, IFN-γ is capable of orchestrating numerous protective functions to heighten immune responses in infections and cancers. It can exhibit its immunomodulatory effects by enhancing antigen processing and presentation, increasing leukocyte trafficking, inducing an anti-viral state, boosting the anti-microbial functions and affecting cellular proliferation and apoptosis. A complex interplay between immune cell activity and IFN-γ through coordinated…
247 Citations
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