Interferon gamma (IFNgamma) & interleukin-4 (IL-4) gene variants & cytokine levels in pulmonary tuberculosis.

@article{Vidyarani2006InterferonG,
  title={Interferon gamma (IFNgamma) & interleukin-4 (IL-4) gene variants & cytokine levels in pulmonary tuberculosis.},
  author={Mohankumar Vidyarani and Paramasivam Selvaraj and S Prabhu Anand and Mohideen S. Jawahar and A. R. Adhilakshmi and P. R. Lekshmi Narayanan},
  journal={The Indian journal of medical research},
  year={2006},
  volume={124 4},
  pages={
          403-10
        }
}
BACKGROUND & OBJECTIVES Cytokine gene polymorphisms may alter Th1/Th2 balance with major implications in tuberculosis. The aim of our study was to find out whether Interferon gamma +874A and IL-4 -590T polymorphisms were associated with susceptibility to pulmonary tuberculosis as well as the level of IFNgamma and IL-4 in south Indian population. METHODS Interferon gamma +874A and IL-4 -590T promoter polymorphisms were studied in 129 pulmonary tuberculosis (PTB) patients and 127 normal healthy… CONTINUE READING

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