Interferon gamma: a master regulator of atherosclerosis.

@article{McLaren2009InterferonGA,
  title={Interferon gamma: a master regulator of atherosclerosis.},
  author={James E. McLaren and Dipak P. Ramji},
  journal={Cytokine & growth factor reviews},
  year={2009},
  volume={20 2},
  pages={125-35}
}
Atherosclerosis is a chronic inflammatory disease that is characterized by the development of fibrotic plaques in the arterial wall. The disease exhibits a complex aetiology and its progression is influenced by a number of environmental and genetic risk factors. The cytokine interferon-gamma (IFN-gamma), a key regulator of immune function, is highly expressed in atherosclerotic lesions and has emerged as a significant factor in atherogenesis. Evidence from both mouse models of atherosclerosis… CONTINUE READING

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