Interferon-beta1b in multiple sclerosis.

  title={Interferon-beta1b in multiple sclerosis.},
  author={Mathias Buttmann and Peter Rieckmann},
  journal={Expert review of neurotherapeutics},
  volume={7 3},
In 1993, interferon (IFN)-beta(1b) for subcutaneous injection became the first US FDA-approved immunomodulatory treatment for multiple sclerosis, a chronic inflammatory disease of the CNS. In this review of IFN-beta(1b), we first present a short introduction to multiple sclerosis and currently available therapeutics. We then summarize current knowledge about the biochemical structure of IFN-beta(1b), as well as pharmacokinetics and pharmacodynamics, including data on putative mechanisms… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 24 extracted citations

IL-10 Modulates Th17 Pathogenicity during Autoimmune Diseases

Journal of clinical & cellular immunology • 2016
View 1 Excerpt

Similar Papers

Loading similar papers…