Interferon-beta induces the development of type 2 dendritic cells.

@article{Huang2001InterferonbetaIT,
  title={Interferon-beta induces the development of type 2 dendritic cells.},
  author={Yu-Min. Huang and Yassir Hussien and Dmitry Yarilin and Baoguo Xiao and Yong Jun Liu and Holger Link},
  journal={Cytokine},
  year={2001},
  volume={13 5},
  pages={
          264-71
        }
}
Suppression of interleukin 12 (IL-12) production by dendritic cells (DCs) has been hypothesized to be a principal mechanism underlying the biological action of interferon (IFN)-beta used for treatment of multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system with possible autoimmune origin. How IFN-beta interacts with DCs to inhibit IL-12 production remains unclear. In this study, we found that DCs derived from human blood monocytes, upon culture in the presence… CONTINUE READING
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