Interferon-beta gene therapy for cancer: basic research to clinical application.

@article{Yoshida2004InterferonbetaGT,
  title={Interferon-beta gene therapy for cancer: basic research to clinical application.},
  author={Jun Yoshida and Masaaki Mizuno and Toshihiko Wakabayashi},
  journal={Cancer science},
  year={2004},
  volume={95 11},
  pages={858-65}
}
Interferon-beta gene therapy for cancer is the first such protocol developed in Japan. Here we describe the development process of our interferon-beta gene therapy from basic research to clinical application. Interestingly, the biological and biochemical characteristics of interferon-beta gene therapy through transfer of the interferon-beta gene into tumor cells by means of cationic liposomes differed from those of conventional interferon-beta protein therapy. Interferon-beta gene transfer… CONTINUE READING

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