Interferon-alpha treatment in multiple myeloma: meta-analysis of 30 randomised trials among 3948 patients.

@article{Fritz2000InterferonalphaTI,
  title={Interferon-alpha treatment in multiple myeloma: meta-analysis of 30 randomised trials among 3948 patients.},
  author={Elke Fritz and Heinz Ludwig},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2000},
  volume={11 11},
  pages={1427-36}
}
BACKGROUND After two decades of interferon (IFN) treatment in myeloma patients and many randomised clinical trials, no definite proof of its benefits exists. This meta-analysis of all available relevant published data tests the differences between IFN and control arms in a large patient population and addresses the issue of cost-effectiveness. PATIENTS AND METHODS Meta-analysis was performed on 17 trials among 2333 patients who received IFN-chemotherapy induction treatment or chemotherapy… CONTINUE READING
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