Interferon-a2b reduces neo-microvascular density in the 'normal' urothelium adjacent to the tumor after transurethral resection of superficial bladder carcinoma.

@article{Giannopoulos2003Interferona2bRN,
  title={Interferon-a2b reduces neo-microvascular density in the 'normal' urothelium adjacent to the tumor after transurethral resection of superficial bladder carcinoma.},
  author={Aris M. Giannopoulos and Ioannis Adamakis and Konstantinos Evangelou and Myrto Giannopoulou and Panayotis Zacharatos and P Zsantoulis and Branko Perunovi{\'c} and Athanasios Athanasiou and George Retalis and Constantinos Constandinidis and Vassilis G Gorgoulis},
  journal={Onkologie},
  year={2003},
  volume={26 2},
  pages={147-52}
}
BACKGROUND As angiogenesis represents one of the hallmarks of cancer we investigated whether intravesically administered interferon-a (IFN-a2b) reduces neo-angiogenesis in the 'normal' urothelium adjacent to the tumor in patients with superficial bladder carcinoma after complete transurethral resection (TUR) of the tumor. PATIENTS AND METHODS In the present study 47 patients after TUR of the tumor were examined. 10 patients (group A) received no further treatment (control group); 37 patients… CONTINUE READING